InterStim II for Sacral Nerve Stimulation

Interstim

Specifications for InterStim II, Model 3058

Height 1.7 in (44 mm)
Length 2.0 in (51 mm)
Thickness 0.3 in (7.7 mm)
Weight 0.8 oz (22 g)
Volume 14 cc
Battery Life 4.4 year average (2.9 - 5.4 year range)
Number of electrodes 4
Rate* 10-14Hz
Pulse Width* 210 μsec
Amplitude* 0-4V
Rechargeable No
Cycling* OFF/ON: 8 s to 16 s
Compatible Leads 28 cm, 33 cm, 41 cm
Number of Screws 1
Lead Insertion Indicator Integrated into lead
Strain Relief Integrated into header
Functional Telemetry Area 105 cm3

* These are typical settings. For more detail, refer to the InterStim II Technical Manual.

Neurostimulator Battery Life: Estimated battery life at high, moderate and low energy consumption*

Description Amp (v) Rate (Hz) Pulsewidth (μs) Mode Electrodes Longevity (years)
High energy 4v 14Hz 210μs Continuous Bipolar, 2 active 2.9
Moderate energy 3v 14Hz 210μs Cycling: 16 s ON, 8 s OFF Bipolar, 2 active 4.4
Low energy 2v 10Hz 210μs Cycling: 16s ON, 8s OFF Bipolar, 2 active 5.4

* These estimations of battery life assume a new neurostimulator with no subsequent adjustments to stimulation parameter. Battery life will be shortened if stimulation parameters are increased to consume more energy. Accurate placement of the InterStim lead will minimize stimulation parameters and energy consumption, thus maximizing battery life.

How It Works

The implantable InterStim® II neurostimulator uses mild electrical stimulation of the sacral nerves to influence the behavior of the bladder, sphincter, and pelvic floor muscles. While anticholinergic drugs address the muscle component in urinary control, the InterStim neurostimulator addresses the nerve component.1-2

In properly selected patients, the InterStim II neurostimulator can dramatically reduce or eliminate symptoms of overactive bladder (OAB) and uninary retention. Mild electrical pulses stimulate those nerves that provide the most distal common autonomic and somatic nerve supply to the pelvic floor and lower urinary tract.3*

*The precise mechanism of action has not been established.

Indications

The treatment of urinary retention and the symptoms of overactive bladder, including urinary urge incontinence and significant symptoms of urgency-frequency alone or in combination, in patients who have failed or could not tolerate more conservative treatments.

References

  1. Siegel SW, Catanzaro F, Dijkema HE, et al. Long-term results of a multicenter study on sacral nerve stimulation for treatment of urinary urge incontinence, urgency-frequency, and retention. Urology. 2000;56(suppl 6A):87-91.
  2. Hashim H, Abrams P. Drug treatment of overactive bladder: efficacy, cost and quality-of-life considerations. Drugs. 2004;64:1643-1656.
  3. InterStim Technical Manual